| 6% CT Blood
(Form 100) | Cohort | HT
DM
(CT) | 8.6%
4.3%
(~6% CT cohort) | 0, 1, 3, 6, 9 | Stratified by CC, hyst (HT), race; oversampling of minorities with goal of equity across clinics (same subsample as Form 80 [for hip/waist], and Form 38- Daily Life. DM subsample same as 4DFR) | Blood analyzed for 20 'core' analytes: micronutrients, glucose, insulin, lipids | | FFQ
(Form 60) | one-time
Rotating cross-sectional | DM | 30%
33% | 2
Annually after year 2 | Stratified by CC | Designed so that each participant is scheduled to complete an FFQ every 3 years after year 2 | | 4DFR
(Form 62) | Cohort | DM | 4.6% | 0, 1 | Overlap with blood subsample in DM | 4DFRs collected, documented, and analyzed on subsample | | 24 Hr Recall | Repeated, cross-sectional
Cohort
| DM
DM | 1%
4.6% | Annually
3, 6, 9 | Selected annually
Same subsample as 4DFR | 24 Hr administered centrally
Note: 24 Hr replaced the 4DFR after year 1 | | Endometrial Aspiration
(Form 82) | Cohort | | 5% | 3, 6, 9 | Stratified by CC | | | Cognitive Function
(Form 39) | Cohort | HT > 65 yrs old | 25% | 0, 1, 3, 6, 9 | Stratified by CC | | | Daily Life
(Form 38) | Cohort | HT
DM | 8.6%
4.3% | 3, 6, 9 | Stratified by CC, hyst (HT), race; oversampling of minorities with goal of equity across clinics (same as blood subsample) | | | Functional Status (Form 90) | | | | | Stratified by CC, selected independently of Cognitive Function subsample | | |
OS-MPS
(Measurement Precision Study)
| | | | |
Stratified by CC, age, race/ethnicity, subject to consent
|
Repeat selected baseline measurements at 3 months, including blood sample
| |
Waist/Hip Circumferences (Form 80)
| | |
8.6%
4.3%
(~6% CT cohort)
| | | | | | | | All participants randomized/enrolled at 3 clinical centers, or about 6-7% of total WHI | Baseline, Y3, Y6, Y9; additional collection at Y1 for CT | Whole body, Hip, and Spine scans at each contact | |
|