This page provides study documentation for consortium study M16. For description of the specimen results, see Specimen Results Description (open to public). Data sets of the specimen results are included in the existing WHI datasets located on the WHI Data on this site (sign in and a completed Data Distribution Agreement are required; see details on the Data site.
Investigator Names and Contact Information
Sylvia Smoller, PhD
Ischemic stroke is a complex genetic disorder. Limited progress has been made to unravel the genetics of ischemic stroke since, until recently, the field has been hampered by inadequate cross-study collaborations that have resulted in multiple studies of small sample size with unsophisticated phenotyping. This application for a genome-wide association study (GWAS), submitted in response to NINDS Funding Opportunity Announcement RFA-NS-09-002, builds on the innovative collaborations established through the International Stroke Genetics Consortium (ISGC). It will greatly advance the field of ischemic stroke genetics by establishing a large 10-study collaboration of unique scale that will bring together the world’s leading clinician-scientists in stroke genetics to generate well-powered genetic investigations with careful, uniform phenotyping.