Investigator Names and Contact Information
Samir Hanash, MD, PhD
Lung cancer is the leading cause of cancer death in the world1. While most cases are attributable to smoking, a significant percentage of female cases, that in some countries is as high as 80%, are not attributable to smoking1-3. Based on 2006 estimates, in the U.S. 10% of lung cancer diagnosed among men (9,270 cases) and 15% (12,265 cases) to 25% (20,442 cases) of those diagnosed among women occur among never smokers4-9. The incidence of lung cancer among never smokers ranges from 14.4 to 20.8 per 100,000 person-years in women and 4.8 to 13.7 per 100,000 person-years in men9. Lung cancer among never smokers also accounts for a significant proportion of lung cancer deaths. Approximately 15% to 20% (17,000 to 26,000 cases per year) of all lung cancer deaths occur in never smokers10.